GUARDIAN AD LITEM, A POTENTIALLY EXPENSIVE INVITATION TO EITHER THE MISMANAGEMENT OR MANAGEMENT OF PATIENTS WITH COGNITIVE DISORDERS

Guardian ad litem, a potentially expensive invitation to either the mismanagement or management of patients with cognitive disorders

Richard F EdlichBiomedical Engineering and Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USAAbstract: The children of a multiple sclerosis (MS) patient filed a guardian ad litem case to be brought against the patient.The basis for the petition was that the MS patient had a significant reduction is his mental compete

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Inhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma

Immunotherapy has recently become a promising cancer therapy with extensive applications of immune checkpoint inhibitors (ICIs).However, pancreatic ductal adenocarcinoma (PDAC) appears to be unresponsive to immunotherapy due to the immunosuppressive microenvironment.Recent studies showed that cancer stem cell marker DCLK1 promoted the initiation an

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